The Mechanisms in Hematology website is suited to senior students, residents, fellows and physicians as an introduction or re-introduction to the basic biology of clinical hematology. The site makes broad use of illustrations to complement the text.
The goal has been to assemble the basic mechanisms of normal and abnormal haematology within a relatively compact space. The descriptions are short, and assemble diffuse information as a brief compendium, with suggested readings intended to lure the learner further into the subject. Topics covered include:

• Cell Signalling
• The Cell Cycle
• Adhesion Molecules
• Apoptosis
• Hematopoiesis, Granulopoiesis, Red Cell Life Span & Bilirubin Metabolism
• Neutrophil Function
• Eosinophils, Basophils and Mast Cells
• Erythropoiesis: The Red Cell, Heme Synthesis, Porphyrin Metabolism and Iron Metabolism
• Blood Cell Antigens
• The Hemoglobin Molecule
• Vitamin B12 and Folate Metabolism
• The Immunoglobulin Molecule
• B Lymphocytes
• T Lymphocytes
• Complement
• Dendritic Cells and Macrophages
• The Myeloid Leukemias
• Lymphoid Leukemias
• Chemotherapeutic Antineoplastics
• Coagulation Cascade
• Regulators of Coagulation
• Factor VIII and Factor IX
• von Willebrand Factor
• Vitamin K
• Fibrinogen, Factor XIII and Fibrinolysis
• Platelet Structure and Function
• Endothelium

Thank for your interest and we hope that you enjoy Mechanisms™ in Hematology. Please send us your feedback.

– The Mechanisms in Medicine Team & Dr. Sara Israels, Editor-in-Chief